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KMID : 0363020050350041109
Journal of Korean Academy of Periodontology
2005 Volume.35 No. 4 p.1109 ~ p.1116
The effect of periodontal therapy on the gingival thickness in patients with drug-induced gingival enlargement
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Abstract
The purpose of this study was to observe the effects of periodontal therapy, including
nonsurgical periodontal therapy with azithromycin, surgical therapy, and maintenace therapy
on the drug-induced gingival enlargement, by means of measuring gingival thickness.
The test group of 18 patients with drug-induced gingival enlargement received scaling, root
planing with azithromycin for 5 days, with or without surgical periodontal treatment. The
control group of 18 patients who had not taken any medication, received scaling and root
planing, with or without surgical periodontal treatment. Both groups received supportive
periodontal therapy every 3 months for 2 years. The mean period of total treatment is 32
months in the test group and 31 months in the control group. The thickness of the buccal
gingiva was measured using an ultrasonic device of SDM¨Þ(Krupp Corp., Essen, Germany).
The results revealed that the test group(1.21¡¾0.51mm) showed statistically thicker buccal
gingiva than the control group(1.01¡¾0.3mm). In the test group, the buccal gingiva was thickest
on 2nd molars and was thinnest on canines of both dental arches. In the control group, the
buccal gingiva was thickest on central incisors in the maxilla and 2nd molars in the mandible,
while the thinnest areas were on canines in the maxilla and 1st premolars in the mandible.
It would be concluded that the periodontal treatment with azithromycin aids in decreasing
the degree of the gingival enlargement but cannot prevent the recurrence completely.2)
KEYWORD
Drug induced gingival enlargement, Gingival thickness
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